期刊
BIOESSAYS
卷 29, 期 11, 页码 1077-1080出版社
WILEY-BLACKWELL
DOI: 10.1002/bies.20669
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资金
- Medical Research Council [MC_U137761446] Funding Source: researchfish
- Medical Research Council [MC_U137761446] Funding Source: Medline
- MRC [MC_U137761446] Funding Source: UKRI
The landscapes of mammalian genomes are characterized by complex patterns of intersecting and overlapping sense and antisense transcription, giving rise to large numbers of coding and non-protein-coding RNAs (ncRNAs). A recent report by Kapranov and colleagues((1)) describes three potentially novel classes of RNAs located at the very edges of protein-coding genes. The presence of RNAs from one of these classes appears to be correlated with the expression levels of their associated genes. These results suggest that a proportion of these RNAs might have roles in the cis-regulation of neighbouring protein-coding genes' expression.
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