期刊
CANCER
卷 110, 期 9, 页码 1900-1910出版社
WILEY
DOI: 10.1002/cncr.23000
关键词
acute myeloid leukemia; new agents; risk stratification; therapy
类别
Significant progress in understanding the mechanisms leading to the development of acute myeloid leukemia (AML) has led to the identification of numerous molecular abnormalities that may be responsible for leukemogenesis. Over the same period, large trials have established standard regimens combining cytotoxic agents for the treatment of patients with AML. Current research is attempting to better stratify, patients by identifying risk factors responsible for resistance, and to discern ways for incorporating newer agents with specific and targeted activity into our standard regimens, Herein the recent developments in the diagnosis and treatment of AML are reviewed.
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