期刊
MATERNAL AND CHILD HEALTH JOURNAL
卷 11, 期 6, 页码 517-525出版社
SPRINGER/PLENUM PUBLISHERS
DOI: 10.1007/s10995-007-0202-7
关键词
infant; low birth weight; pregnancy complications; premature birth; assisted reproductive technology
Objective: To assess associations between assisted reproductive technology (ART) and adverse maternal and infant outcomes, with an emphasis on singletons. Methods: We linked data from the US ART surveillance system with Massachusetts live birth-infant death records data for resident births in 1997-1998 and compared births conceived with ART (N = 3316) with births not conceived with ART or infertility medications (N = 157,066) on: maternal chronic conditions, pregnancy complications, labor and delivery complications, and perinatal and infant outcomes. Results: Overall, ART was strongly associated with numerous adverse outcomes. The magnitude was reduced for several outcomes when analyses were limited to singletons. After further exclusion of maternal subsets with rare ART births (maternal age <20; education
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