4.4 Article Proceedings Paper

Neurotoxicity of tryptophan metabolites

期刊

BIOCHEMICAL SOCIETY TRANSACTIONS
卷 35, 期 -, 页码 1287-1289

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PORTLAND PRESS LTD
DOI: 10.1042/BST0351287

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cerebellar granule neuron; 5-hydroxyanthranilic acid; 3-hydroxykynurenine kyriunenine; quinciinic acid; tryptophan metabolite

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The metabolism of tryptophan by the kynurenine pathway leads to the production of several neurotoxic compounds, some of which have been associated with neurological disorders. Recent investigation of some relevant compounds in this pathway has provided further evidence of their neurotoxicity.

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