期刊
ACS NANO
卷 1, 期 4, 页码 265-272出版社
AMER CHEMICAL SOC
DOI: 10.1021/nn700130f
关键词
carbon nanohorns; light-assisted oxidation; modification; dispersion; drug delivery
We show that light-assisted oxidation with hydrogen peroxide effectively and rapidly opens holes in carbon nanohorn walls and, more importantly, creates abundant oxygenated groups such as carboxylic groups at the hole edges. These oxygenated groups reacted with the protein bovine serum albumin. The obtained conjugates were highly dispersed in phosphate-buffered saline and were taken up by cultured mammalian cells via an endocytosis pathway.
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