期刊
CARBOHYDRATE RESEARCH
卷 342, 期 15, 页码 2297-2302出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.carres.2007.06.027
关键词
sulfonamidoglycosylation; glycals; sulfonamides; ferrier rearrangement
A series of novel N-glycosyl sulfonamides were prepared via Ferrier sulfonamidoglycosylation of D-glycals with good to high alpha-stereo selectivity. Two new glycosylsulfamides were tested as carbonic anhydrase (CA II) inhibitors and showed good properties in the micromolar range. (C) 2007 Elsevier Ltd. All rights reserved.
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