期刊
JOURNAL OF CHEMICAL PHYSICS
卷 127, 期 17, 页码 -出版社
AMER INST PHYSICS
DOI: 10.1063/1.2784557
关键词
-
资金
- NIGMS NIH HHS [GM076689] Funding Source: Medline
- NINDS NIH HHS [1 R21 NS058604-01] Funding Source: Medline
We develop a numerical scheme that calculates forces under given conformational states of a biomolecule by using a harmonic sampling potential. It can also be used for calculating the potential of mean force, as tested by random walks on Gaussian enthalpy barriers. Further, Brownian dynamics simulations of a finite-length freely jointed chain confirm the analytic expressions for its entropic elasticity that we derive. Our method, while generally applicable to many systems, will be particularly useful for studying the elasticity of biopolymers where various types of ensembles differ due to the finite size effect.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据