4.8 Article

Olefin metathesis in homogenous aqueous media catalyzed by conventional ruthenium catalysts

期刊

ORGANIC LETTERS
卷 9, 期 23, 页码 4885-4888

出版社

AMER CHEMICAL SOC
DOI: 10.1021/ol7022505

关键词

-

资金

  1. NCRR NIH HHS [P41 RR 02301, P41 RR002301] Funding Source: Medline
  2. NIGMS NIH HHS [GM 44783, R01 GM044783-17, R01 GM044783] Funding Source: Medline

向作者/读者索取更多资源

Olefin metathesis in aqueous solvents is sought for applications in green chemistry and with the hydrophilic substrates of chemical biology, such as proteins and polysaccharides. Most demonstrations of metathesis in water, however, utilize exotic complexes. We have examined the performance of conventional catalysts in homogeneous water/organic mixtures, finding that the second-generation Hoveyda-Grubbs catalyst has extraordinary efficiency in aqueous dimethoxyethane and aqueous acetone. High (71-95%) conversions are achieved for ring-closing and cross metathesis of a variety of substrates in these solvent systems.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.8
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据