期刊
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
卷 33, 期 -, 页码 132-134出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.ijid.2015.01.011
关键词
Double carbapenem; Colistin; Pan-drug resistant K. pneumoniae; Bloodstream infection
资金
- Sapienza University of Rome
Infections due to carbapenemase-producing Klebsiella pneumoniae represent an emerging threat due to the high mortality rate and lack of valid antimicrobial combinations, especially when the strain is colistin-resistant. We report a case of bloodstream infection due to pandrug-resistant K. pneumoniae treated successfully with an innovative regimen comprising a combination of colistin plus double carbapenem, along with an in vitro analysis showing the synergistic and bactericidal effect. (C) 2015 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.
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