期刊
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
卷 32, 期 -, 页码 94-100出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.ijid.2015.01.014
关键词
Tuberculosis; Drug resistance; Molecular mechanisms of resistance
资金
- FCT, Portugal [SFRH/BD/70037/2010]
- Fundação para a Ciência e a Tecnologia [SFRH/BD/70037/2010] Funding Source: FCT
Multidrug-resistant and extensively drug-resistant tuberculosis (TB) represent a major threat to the control of the disease worldwide. The mechanisms and pathways that result in the emergence and subsequent fixation of resistant strains of Mycobacterium tuberculosis are not fully understood and recent studies suggest that they are much more complex than initially thought. In this review, we highlight the exciting new areas of research within TB resistance that are beginning to fill these gaps in our understanding, whilst also raising new questions and providing future directions. (c) 2015 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.
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