期刊
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
卷 73, 期 23, 页码 7767-7770出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AEM.01477-07
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Fluorescence in situ hybridization and real-time PCR analysis targeting the 16S rRNA gene of Akkermansia muciniphila were performed to determine its presence in the human intestinal tract. These techniques revealed that an A. muciniphila-like bacterium is a common member of the human intestinal tract and that its colonization starts in early life and develops within a year to a level close to that observed in adults (10(8) cells/g) but decreases (P < 0.05) in the elderly.
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