期刊
MOLECULAR AND BIOCHEMICAL PARASITOLOGY
卷 156, 期 2, 页码 93-101出版社
ELSEVIER
DOI: 10.1016/j.molbiopara.2007.07.007
关键词
trypanosoma; Leishmania; mRNA; degradation; translation
资金
- Wellcome Trust Funding Source: Medline
Gene expression in Kinetoplastids is very unusual in that the open reading frames are arranged in long polycistronic arrays, monocistronic mRNAs being created by post-transcriptional processing. Thus the regulation of gene expression is post-transcriptional. We here discuss recent results concerning the enzymes required for mRNA degradation, and components of the translation initiation machinery, and how both are regulated. (c) 2007 Elsevier B.V. All rights reserved.
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