期刊
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
卷 29, 期 12, 页码 1090-1101出版社
WILEY
DOI: 10.1002/hed.20639
关键词
head and neck cancer; Charlson comorbidity index; Kaplan-Feinstein index; ASA; complications
Background. Free flap reconstruction of head and neck cancer defects is complex with many factors that influence perioperative complications. The aim was to determine if there was an association between perioperative variables and postoperative outcome. Methods. We evaluated 185 patients undergoing free flap reconstruction following ablation of head and neck cancer between 1999 and 2001. Demographic, laboratory, surgical and anesthetic variables were analyzed using univariate and multivariable techniques. Results. Ninety-eight patients (53%) developed complications, of which 74 were considered major, giving a major morbidity rate of 40%. Predictors of major complications were increasing patient age, ASA class, and smoking. Predictors of medical complications were ASA class, smoking, age and crystalloid replacement, Predictors of surgical complications were tracheostomy, preoperative hemoglobin, and preoperative radiotherapy. Conclusion, Patient age, comorbidity, smoking, preoperative hemoglobin, and perioperative fluid management are potential predictors of postoperative complications following free flap reconstruction for cancer of the head and neck. (c) 2007 Wiley Periodicals, Inc.
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