期刊
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
卷 89, 期 3, 页码 498-500出版社
AMER SOC TROP MED & HYGIENE
DOI: 10.4269/ajtmh.12-0599
关键词
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资金
- European Union [EU FP6 2003-INCO-Dev2-015476, FP7 241500]
- the Netherlands Organisation for Scientific Research
- Buruli ulcer Groningen Foundation
Neopterin is closely associated with activation of the cellular immune system. Neopterin levels differed between controls and patients with Buruli ulcer disease. No differences between patients with or without paradoxical responses were observed. Therefore, neopterin has no value in detecting paradoxical responses among patients with limited Buruli ulcer disease. Neopterin levels were lower in patients receiving clarithromycin. This finding might indicate a slower cellular immune recovery, with possible consequences in future therapy with clarithromycin.
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