Thermodynamic and kinetic considerations on the specific adsorption and molecular recognition by molecularly imprinted polymer

This article presents an original work on thermodynamically and kinetically interpreting the specific adsorption and recognition by molecularly imprinted polymer. The imprinted polymer was prepared with Bisphenol A (BPA) dimethacrylate as template monomer. The results indicate that the prepared polymer can well discriminate the template from its analogue, so as to adsorb more for BPA and less for DHBP. Kinetic analysis indicates that this specific adsorption, in nature, can be a result of preferential promotion. The imprint leads to a larger adsorption-rate in the template than in its analogue. Thermodynamic study also implies that the molecular induction of imprint toward BPA is larger than toward DHBP, which thus makes the polymer capable of specifically allowing the template to bind.