4.5 Article

Short Report: Active Case Detection with Pooled Real-Time PCR to Eliminate Malaria in Trat Province, Thailand

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AMER SOC TROP MED & HYGIENE
DOI: 10.4269/ajtmh.2012.11-0617

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  1. Bill & Melinda Gates Foundation
  2. Bureau of Vector-Borne Diseases, Department of Disease Control, Ministry of Public Health, Thailand
  3. University of North Carolina Entrepreneurial Public Service from the Carolina Center for Public Service at the University of North Carolina at Chapel Hill

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We conducted contact tracing and high-risk group screening using pooled real-time polymerase chain reaction (PCR) to support malaria elimination in Thailand. PCR detected more Plasmodium infections than the local and expert microscopists. High-throughput pooling technique reduced costs and allowed prompt reporting of results.

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