期刊
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
卷 85, 期 2, 页码 257-264出版社
AMER SOC TROP MED & HYGIENE
DOI: 10.4269/ajtmh.2011.10-0516
关键词
-
资金
- Innovative Vector Control Consortium
- Department of Homeland Security, and Fogarty International Center, National Institutes of Health
Models can be useful tools for understanding the dynamics and control of mosquito-borne disease. More detailed models may be more realistic and better suited for understanding local disease dynamics; however, evaluating model suitability, accuracy, and performance becomes increasingly difficult with greater model complexity. Sensitivity analysis is a technique that permits exploration of complex models by evaluating the sensitivity of the model to changes in parameters. Here, we present results of sensitivity analyses of two interrelated complex simulation models of mosquito population dynamics and dengue transmission. We found that dengue transmission may be influenced most by survival in each life stage of the mosquito, mosquito biting behavior, and duration of the infectious period in humans. The importance of these biological processes for vector-borne disease models and the overwhelming lack of knowledge about them make acquisition of relevant field data on these biological processes a top research priority.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据