期刊
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
卷 83, 期 5, 页码 1066-1069出版社
AMER SOC TROP MED & HYGIENE
DOI: 10.4269/ajtmh.2010.10-0306
关键词
-
资金
- National Institutes of Health [K08 HL094759]
- Wellcome Trust
Melioidosis is a frequently lethal tropical infection caused by the environmental saprophyte Burkholderia pseudomallei Although transcutaneous inoculation and inhalation arc considered the primary routes of infection suggestive clinical evidence implicates ingestion as a possible alternative route We show that in BALB/c and C57BL/6 mice direct gastric inoculation of high doses of B pseudomaller, causes systemic infection that may be lethal or cause chronic disseminated infection Mice may shed bacteria in the stool for weeks after infection and high titers of B pseudomaller specific IgG are detectable This report of enteric murine melioidosis supports further consideration of this route of infection
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据