期刊
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
卷 79, 期 5, 页码 708-714出版社
AMER SOC TROP MED & HYGIENE
DOI: 10.4269/ajtmh.2008.79.708
关键词
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资金
- ICDDR,B [U01 AI058935, RO3 AI063079, R01 AI40725]
- Swedish Agency for Research and Economic Cooperation [2004-0578]
- Fogarty International Center at the National Institutes of Health [D43 TW005572]
Bangladesh experienced severe flooding and diarrheal epidemics in 2007. We compared flood data from 2007 with 2004 and 1998 for diarrheal patients attending the ICDDR,B hospital in Dhaka. In 2007, Vibrio cholerae OI (33%), rotavirus (42%), and enterotoxigenic Escherichia coli (ETEC) (12%) were most prevalent. More severe dehydration was seen in 2007 compared with 2004 and 1998 (P < 0.001). In 2007, V. cholerae OI Inaba (52%) and Ogawa (48%) were seen, whereas in 2004 and 1998 it was primarily Inaba and the Ogawa types, respectively (P < 0.001). In 2007, 51% of ETEC produced the heat labile toxin (LT) (P < 0.001 compared with 2004), 22% expressed the heat stable (ST) (P < 0.001). and 27% were ST/LT positive (P = 0.231). The CS7 colonization factor (CF) was the most prevalent in 2007 (20% compared with 6% in 2004; P = 0.05). Our findings demonstrate alterations in clinical features and phenotypic changes of major bacterial pathogens in the recent Bangladesh flood.
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