期刊
AMERICAN JOURNAL OF TRANSPLANTATION
卷 11, 期 7, 页码 1488-1497出版社
WILEY
DOI: 10.1111/j.1600-6143.2011.03598.x
关键词
Basal cell carcinoma; cardiac transplant; database; epidemiology; melanoma; nonmelanoma skin cancer; organ transplantation; skin cancer; squamous cell carcinoma
资金
- Northwestern University
- Cardiac Transplant Research Database research funds
Skin cancer incidence has been shown to be increased in the context of transplant-associated immunosuppression. There is, however, limited information specifically about the incidence of skin cancer after cardiac transplantation in the United States. A 10-year retrospective cohort study of 6271 heart transplants at 32 US transplant centers revealed increased post-procedure incidence of nonmelanoma and melanoma skin cancers, especially cutaneous squamous cell carcinoma, for which the incidence increased from 4- to 30-fold compared to the age and gender equivalent general population. Incidence of skin cancer in this study was consistent with prior single-center data regarding cardiac transplant patients. Comparison of all-cause mortality statistics for patients with basal cell carcinoma, squamous cell carcinoma and melanoma, respectively, demonstrated increased mortality associated with melanoma. Skin cancer screening and prophylaxis may be of some utility in reducing morbidity and mortality in cardiac transplant patients.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据