期刊
ATHEROSCLEROSIS
卷 195, 期 2, 页码 E190-E194出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.atherosclerosis.2007.06.021
关键词
Arterial stiffness; Aortic atherosclerosis; Applanation tonometry; Transesophageal echocardiography
Both increased arterial stiffness and atherosclerosis are risk factors for cardiovascular morbidity and mortality. We studied the relationship between aortic atherosclerosis, assessed by measuring maximal aortic intima-media thickness (MAIMT) on transesophageal echocardioagraphy and aortic stiffness, measured by applanation tonometry. Eighty-one patients (28 men, 53 women, mean age 61 +/- 13 years) referred for transesophageal echocardiography were studied. Augmentation index (AI) and carotid-radial pulse (PWV) wave velocity were measured using a SphygmoCor (R) tonometer (Atcor Med., Australia). MAIMT was correlated with AI and age (r = 0.35, p = 0.002 and r = 0.36, p = 0.001), respectively. There were no relations between MAIMT and either aortic pulse pressure (A-PP) (r = 0.10, p = 0.35) or PVW (r = -0.38, p = 0.76). Multivariate regression analysis revealed that AI and age were independently related to MAIMT. In this middle-aged predominantly African-American population structural aortic atherosclerosis and aortic stiffness as measured by AI are age dependent and are inter-related, independent of age. (C) 2007 Elsevier Ireland Ltd. All rights reserved.
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