期刊
JOURNAL OF NATURAL PRODUCTS
卷 70, 期 12, 页码 2029-2032出版社
AMER CHEMICAL SOC
DOI: 10.1021/np070327e
关键词
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Three new flavonoid glycosides (1-3), 11-hydroxyhainanolidol (4), and a new dibenzylbutyrolactone lignan glycoside (5) were isolated from the aerial parts of Cephalotaxus koreana Nakai, along with 19 known flavonoids. The structures of the new compounds were elucidated using spectroscopic evidence, primarily NMR and MS. Twenty-four compounds were isolated, and among these isoscutellarein 5-O-beta-D-glucopyranoside (3), apigenin (6), kaempferol 3-O-alpha-L-rhamnopyranosyl(l'-> 6)-beta-D-glucopyranoside (7), tamarixetin 3-O-alpha-L-rhamnopyranosyl(l'-> 6)-beta-D-glucopyranoside (8), quercetin 3-O-[6-O-acetyl]-beta-D-glucopyranoside (9), and quercetin 3-O-alpha-L-rhamnopyranoside (10) showed significant inhibitory activities against osteoclast differentiation at concentrations of 0.1 and 1.0 mu g/mL.
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