期刊
VACCINE
卷 25, 期 50, 页码 8480-8485出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.vaccine.2007.08.061
关键词
yellow fever; yellow fever vaccine-associated viscerotropic disease; yellow fever vaccination
Yellow fever vaccine-associated viscerotropic disease (YEL-AVD) is a rare complication of yellow fever (YF) vaccination. A previously healthy 22-year-old female died following YF vaccination despite aggressive measures. Serial viral load titers, cytokine levels and host genetic factors were evaluated in an attempt to understand this unusual and lethal outcome. The patient's high-titer vaccine viremia and possibly related minor genetic anomalies provide clues to exploring the etiology of YEL-AVD. (c) 2007 Elsevier Ltd. All rights reserved.
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