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Radical reactions in aqueous medium using (Me3Si)3SiH

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卷 9, 期 25, 页码 5159-5162

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AMER CHEMICAL SOC
DOI: 10.1021/ol7020803

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(Me3Si)(3)SiH was used as a successful reagent in a variety of radical-based transformations in water. The system comprising substrate, silane, and initiator (ACCN) mixed in aqueous medium at 100 degrees C worked well for both hydrophilic and hydrophobic substrates, with the only variation that an amphiphilic thiol was also needed in case of the water-soluble compounds.

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