期刊
ORGANIC LETTERS
卷 9, 期 26, 页码 5521-5524出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol7024718
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资金
- NIGMS NIH HHS [GM58160] Funding Source: Medline
A modular and practical synthesis of highly substituted oxazoles has been developed. The transformation consists of a sequential copper-catalyzed amidation of vinyl halides followed by cyclization promoted by iodine. A wide variety of functionalized oxazoles and polyazoles can be obtained in a selective manner from simple and easily accessible precursors.
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