期刊
JOURNAL OF MEDICINAL CHEMISTRY
卷 50, 期 26, 页码 6443-6445出版社
AMER CHEMICAL SOC
DOI: 10.1021/jm701186z
关键词
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A novel, potent series of indole analogs were recently developed as MR antagonists, culminating in 14. This compound represents the first MR antagonist in this class of molecules, exhibiting picomolar binding affinity and in vivo blood pressure lowering at pharmaceutically relevant doses.
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