Microcalcifications Around a Collagen-Based Breast Biopsy Marker: Complication of Biopsy With a Percutaneous Marking System

OBJECTIVE. The purpose of this article is to present the cases of four women who underwent percutaneous breast biopsy with deployment of a titanium metallic marker embedded in a bioresorbable collagen plug. Routine follow-up mammography after benign pathologic results were obtained revealed new fine microcalcifications at the biopsy sites, requiring repeat biopsy. Pathologic examination confirmed the presence of microcalcifications associated with an acidophilic foreign material. CONCLUSION. Awareness that development of microcalcifications can complicate biopsy performed with collagen-based markers is important for correct mammographic interpretation and management.