期刊
AMERICAN JOURNAL OF ROENTGENOLOGY
卷 195, 期 1, 页码 13-28出版社
AMER ROENTGEN RAY SOC
DOI: 10.2214/AJR.10.4392
关键词
gadoxetate disodium-enhanced MRI; hepatocyte-specific contrast agent; liver lesion
OBJECTIVE. The purpose of this article is to review the pharmacokinetic and pharmacodynamic properties of gadoxetate disodium (Gd-EOB-DTPA), to describe a workflow-optimized pulse sequence protocol, and to illustrate the imaging appearance of focal lesions in the noncirrhotic liver. CONCLUSION. Gd-EOB-DTPA allows a comprehensive evaluation of the liver with the acquisition of both dynamic and hepatocyte phase images. This provides potential additional information, especially for the detection and characterization of small liver lesions. However, protocol optimization is necessary for improved image quality and workflow.
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