期刊
CLINICAL AND EXPERIMENTAL IMMUNOLOGY
卷 151, 期 2, 页码 199-209出版社
WILEY
DOI: 10.1111/j.1365-2249.2007.03552.x
关键词
alternative pathway of complement; complement factor H; haemolytic uraemic syndrome; membranoproliferative glomerulonephirtis; nephritic factors
类别
资金
- NIDDK NIH HHS [DK71221, R21 DK071221] Funding Source: Medline
Genetic and acquired abnormalities in complement factor H (CFH) have been associated with two different human renal diseases: haemolytic uraemic syndrome and membrano proliferative glomerulonephritis. The new genetic and pathogenetic findings in these diseases and their clinical implications for the management and cure of patients are reviewed in this paper.
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