期刊
AMERICAN JOURNAL OF RHINOLOGY & ALLERGY
卷 23, 期 5, 页码 549-552出版社
SAGE PUBLICATIONS INC
DOI: 10.2500/ajra.2009.23.3366
关键词
Endoscopic sinus surgery; nasal crusting; postoperative infections; sinus cavity infections; Staphylococcus aureus; surgical outcomes; wound healing
Background: Differentiating normal nasal discharge and postoperative crust from infection after endoscopic sinus surgery (ESS) can be difficult. We investigated whether bacteria cultured at operation was predictive for postoperative mucosal infection-defined as frank pits, thick mucus, and/or abnormal crusting seen on endoscopic examination associated with Positive microbiology. Methods: The records of 48 patients with chronic rhinosinusitis (CRS) with infection at the time of ESS were retrospectively reviewed. Results of intraoperative cultures were compared with those taken at the time of postoperative mucosal infection. Results: Fourteen of 16 patients (87.5%) with intraoperative infection With Staphylococcus aureus progressed to postoperative mucosal infection with S. aureus, whereas patients who cultured other bacteria intraoperatively progressed to postoperative mucosal infection in 6119 cases (31.6%), with S. aureus cultured in only 3/19 cases (15.8%; p = 0.0001). Conclusion: S. aureus infection at ESS predicts for abnormal, S. aureus-associated mucosal healing and infection post-ESS. Although a prospective trial is warranted, these findings suggest a future role for aggressive anti-S. aureus therapy peri- and/or postoperatively in patients who culture positive for this organism to improve postsurgical outcomes. (Am J Rhinol Allergy 23, 549-552, 2009; doi: 10.2500/ajra.2009.23.3366)
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