期刊
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
卷 74, 期 5, 页码 1634-1638出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AEM.02512-07
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资金
- NIAID NIH HHS [R01 AI043987, AI43987] Funding Source: Medline
Several Legionella pneumophila proteins were highly expressed in low-temperature supernatants. One of these proteins was the peptidyl-prolyl isomerase PpiB. Mutants lacking ppiB exhibited reduced growth at 17 degrees C. Since PpiB lacked a signal sequence and was present in 17 degrees C supernatants of type II and type IV secretion mutants, this protein may be secreted by a novel mechanism.
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