期刊
EUKARYOTIC CELL
卷 7, 期 3, 页码 546-549出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/EC.00437-07
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资金
- NIAID NIH HHS [R21 AI073380, AI073380] Funding Source: Medline
- NIGMS NIH HHS [R01 GM071007, GM71007] Funding Source: Medline
The fungal pathogen Cryptococcus neoformans regulates its polysaccharide capsule depending on environmental stimuli. To investigate whether capsule polymers change under different growth conditions, we analyzed shed capsules at physiological concentrations without physical perturbation. Our results indicate that regulation of capsule size is mediated at the level of individual polysaccharide molecules.
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