期刊
INTERNATIONAL JOURNAL OF HEMATOLOGY
卷 101, 期 5, 页码 452-466出版社
SPRINGER JAPAN KK
DOI: 10.1007/s12185-015-1785-1
关键词
Acute GVHD (graft-versus-host disaese); Chronic GVHD; Treatment of GVHD
类别
Graft-versus-host disease (GVHD) remains as the major obstacle for successful hematopoietic stem cell transplant (HSCT). Roughly half of the patients undergoing HSCT develop GVHD which requires treatment, and above 10 % of the patient may die because of it. However, GVHD presents with anti-tumor activity, called graft-versus-tumor (GVT) effect, and it carries significant anti-tumor activity, thus suppressing GVHD completely may increase the relapse of original disease. Thus, it is important to control GVHD to the appropriate level.
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