A Randomized Controlled Trial for Reducing Risks for Sexually Transmitted Infections Through Enhanced Patient-Based Partner Notification

Objectives. We sought to assess the effectiveness of approaches targeting improved sexually transmitted infection (STI) sexual partner notification through patient referral. Methods. From January 2002 through December 2004, 600 patients with Neisseria gonorrhoeae or Chlamydia trachomatis were recruited from STI clinics and randomly assigned to either a standard-of-care group or a group that was counseled at the time of diagnosis and given additional follow-up contact. Participants completed an interview at baseline, 1 month, and 6 months and were checked at 6 months for gonorrhea or chlamyclial infection via nucleic acid amplification testing of urine. Results. Program participants were more likely to report sexual partner notification at 1 month (86% control, 92% intervention; adjusted odds ratio [AOR] = 1.8; 95% confidence interval [CI]=1.02, 3.0) and were more likely to report no unprotected sexual intercourse at 6 months (38% control, 48% intervention; AOR=1.5; 95% CI=11.1, 2.1). Gonorrhea or chlamyclial infection was detected in 6% of intervention and 11% of control participants at follow-up (AOR=2.2; 95% CI=1.1, 4.1), with greatest benefits seen among men (for gender interaction, P=.03). Conclusions. This patient-based sexual partner notification program can help reduce risks for subsequent STIs among urban, minority patients presenting for care at STI clinics. (Am J Public Health. 2009;99:S104-S110. doi:10.2105/AJPH.2007.112128)