相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Long-term Incubation with Proteasome Inhibitors (PIs) Induces IκBα Degradation via the Lysosomal Pathway in an IκB Kinase (IKK)-dependent and IKK-independent Manner
Kyoung-Hee Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Phase 2 study of frontline bortezomib in patients with advanced non-small cell lung cancer
Benjamin Besse et al.
LUNG CANCER (2012)
SNX-2112, a Novel Hsp90 Inhibitor, Induces G2/M Cell Cycle Arrest and Apoptosis in MCF-7 Cells
Shao-Xiang Wang et al.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2011)
The Hsp90 inhibitor IPI-504 overcomes bortezomib resistance in mantle cell lymphoma in vitro and in vivo by down-regulation of the prosurvival ER chaperone BiP/Grp78
Gael Roue et al.
BLOOD (2011)
Proteasome Inhibitor PS-341 (Bortezomib) Induces Calpain-dependent IκBα Degradation
Chunyang Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Regulation and Function of NF-kappa B Transcription Factors in the Immune System
Sivakumar Vallabhapurapu et al.
ANNUAL REVIEW OF IMMUNOLOGY (2009)
Bortezomib induces canonical nuclear factor-κB activation in multiple myeloma cells
Teru Hideshima et al.
BLOOD (2009)
Targeting PI3K signalling in cancer: opportunities, challenges and limitations
Jeffrey A. Engelman
NATURE REVIEWS CANCER (2009)
Molecular basis of bortezomib resistance:: proteasome subunit β5 (PSMB5) gene mutation and overexpression of PSMB5 protein
Ruud Oerlemans et al.
BLOOD (2008)
Inhibition of Hsp90 down-regulates mutant epidermal growth factor receptor (EGFR) expression and sensitizes EGFR mutant tumors to paclitaxel
Ayana Sawai et al.
CANCER RESEARCH (2008)
The platelet-derived growth factor receptor α is destabilized by geldanamycins in cancer cells
Daniela Matei et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Proteasome inhibitors induce a p38 mitogen-activated protein kinase (MAPK)-dependent anti-apoptotic program involving MAPK phosphatase-1 and Akt in models of breast cancer
Yue Y. Shi et al.
BREAST CANCER RESEARCH AND TREATMENT (2006)
Proteasome inhibitors induce death but activate NF-κB on endometrial carcinoma cell lines and primary culture explants
Xavier Dolcet et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Bortezomib induces in HepG2 cells IκBα degradation mediated by caspase-8
Giuseppe Calvaruso et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2006)
Antimyeloma activity of heat shock protein-90 inhibition
CS Mitsiades et al.
BLOOD (2006)
A central role for the Hsp90.Cdc37 molecular chaperone module in interleukin-1 receptor-associated-kinase-dependent signaling by toll-like receptors
D De Nardo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Combined proteasome and histone deacetylase inhibition in non-small cell lung cancer
CE Denlinger et al.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2004)
Proteasome inhibition with PS-341 (bortezomib) in lung cancer therapy
PN Lara et al.
SEMINARS IN ONCOLOGY (2004)
Proteasome inhibition sensitizes non-small-cell lung cancer to gemcitabine-induced apoptosis
CE Denlinger et al.
ANNALS OF THORACIC SURGERY (2004)
WNT and β-catenin signalling:: Diseases and therapies
RT Moon et al.
NATURE REVIEWS GENETICS (2004)
Use of methotrexate-based peptide substrates to characterize the substrate specificity of Prostate-Specific Membrane Antigen (PSMA)
A Mhaka et al.
CANCER BIOLOGY & THERAPY (2004)
Effects of the proteasome inhibitor bortezomib alone and in combination with chemotherapy in the A549 non-small-cell lung cancer cell line
MM Mortenson et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2004)
Molecular mechanisms mediating antimyeloma activity of proteasome inhibitor PS-341
T Hideshima et al.
BLOOD (2003)
Molecular sequelae of proteasome inhibition in human multiple myeloma cells
N Mitsiades et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function
AD Basso et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)