期刊
JOURNAL OF LARYNGOLOGY AND OTOLOGY
卷 122, 期 8, 页码 824-828出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0022215107000710
关键词
botulinum toxin; larynx; voice disorder; granuloma; vocal cord
Objective: This study evaluated the role of botulinum toxin type A in the treatment of refractory laryngeal granulomas. Study design and setting: Retrospective clinical review at a tertiary care hospital. Seven patients with vocal process granulomas underwent percutaneous injection of botulinum toxin into both vocal folds, performed in an office setting. Total doses ranged from 10 to 25 U, divided between both vocal folds. Results: All patients experienced resolution of their granulomas over two to seven weeks. No patient developed aspiration pneumonia. All patients experienced hoarseness secondary to the injections, but voice quality returned to baseline in all patients as the toxin was degraded. Conclusions: Botulinum toxin is safe and effective therapy in resolving vocal process granulomas in patients refractory to traditional therapy. The optimal treatment dose remains to be determined. Significance: Percutaneous botulinum toxin injection is helpful in resolving laryngeal granulomas.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据