期刊
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
卷 198, 期 3, 页码 -出版社
MOSBY-ELSEVIER
DOI: 10.1016/j.ajog.2007.11.044
关键词
lactation; metabolic syndrome; parity
资金
- NIA NIH HHS [U01 AG012554, AG012546, AG012535, AG012505, U01 AG012495-06, AG012553, U01 AG012531-14, U01 AG012539-14, U01 AG012505-14, U01 AG012535-06, U01 AG012553-07, U01 AG012535-14, AG012554, AG012539, U01 AG012535-10S2, U01 AG012554-06, U01 AG012546-09S4, AG012531, U01 AG012535, U01 AG012553, U01 AG012539, AG012495, U01 AG017719-01, U01 AG012546, U01 AG012495, U01 AG012505, U01 AG012531, U01 AG017719] Funding Source: Medline
- NINR NIH HHS [U01 NR004061-06, U01 NR004061, NR004061] Funding Source: Medline
OBJECTIVE: The objective of the study was to evaluate whether lactation duration is associated with lower prevalence of metabolic syndrome (MetSyn) in midlife, parous women. STUDY DESIGN: This was a cross-sectional cohort analysis of 2516 parous, midlife women using multivariable logistic regression to determine the independent association of lactation and lactation duration on prevalence of MetSyn. RESULTS: One thousand six hundred twenty women (64.4%) reported a history of breast-feeding, with average lifetime duration of lactation of 1.16 (+/- 1.04) years. MetSyn was present in 536 women (21.3%). Adjusting for age, smoking history, parity, ethnicity, socioeconomic status, study site, physical activity, caloric intake, and high school body mass index, women with prior lactation had significantly lower odds of MetSyn ( odds ratio [OR] 0.79, 95% confidence interval [CI] 0.63 to 0.99). Furthermore, increasing duration of lactation was similarly associated with lower odds of MetSyn (OR 0.88, 95% CI 0.77 to 0.99). CONCLUSION: Duration of lactation is associated with lower prevalence of MetSyn in a dose-response manner in midlife, parous women.
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