期刊
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
卷 198, 期 4, 页码 -出版社
MOSBY-ELSEVIER
DOI: 10.1016/j.ajog.2007.09.028
关键词
gestational diabetes; obesity; weight gain
资金
- NIDDK NIH HHS [R01 DK 54834, R01 DK054834, R01 DK054834-01A1] Funding Source: Medline
OBJECTIVE: The objective of the study was to evaluate obesity and rate of weight change during the 5 years before pregnancy and risk of gestational diabetes mellitus (GDM) in a nested case-control study. STUDY DESIGN: GDM cases (n = 251) and controls (n = 204) were selected from a multiethnic cohort of 14,235 women who delivered a live birth between 1996 and 1998. Women who gained or lost weight were compared with those with a stable weight (+/- 1.0 kg/year). RESULTS: Women who gained weight at a rate of 1.1 to 2.2 kg/year had a small increased risk of GDM (odds ratio [OR] 1.63 [95% confidence interval (CI) 0.95 to 2.81]) and women who gained weight at a rate of 2.3 to 10.0 kg/year had a 2.5-fold increased risk of GDM (OR 2.61 [95% CI, 1.50 to 4.57]), compared with women with stable weight (after adjusting for age, race-ethnicity, parity, and baseline body mass index). CONCLUSION: Weight gain in the 5 years before pregnancy may increase the risk of GDM.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据