Nonocclusive Mesenteric Ischemia in a Dialysis Patient With Extensive Vascular Calcification

We describe a case of nonocclusive mesenteric ischemia in a 37-year-old man with hemodialysis-dependent chronic kidney disease due to diabetes who was admitted to our hospital with abdominal pain. A plain radiograph of the abdomen showed distended loops of small bowel and gas in the hepatic portal vein. Multidetector computed tomography showed massive wall calcification of the superior mesenteric artery and its collaterals, pneumatosis intestinalis of a segment of the jejunum, and porto-mesenteric vein gas. Urgent laparotomy confirmed segmental necrosis of the jejunum, which was resected. Pathologic examination showed whole-layer necrosis of the resected bowel without arterial or venous thrombosis. Nonocclusive mesenteric ischemia is an increasingly recognized and potentially lethal complication in hemodialysis patients. In the present case, critical factors for the development of nonocclusive mesenteric ischemia may have included prolonged hypotension during hemodialysis treatments that reduced blood flow to the small bowel and massive vascular calcification that negatively affected compliance of the superior mesenteric artery and its branches. Am J Kidney Dis. 60(5):843-846. (C) 2012 by the National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.