期刊
AMERICAN JOURNAL OF INDUSTRIAL MEDICINE
卷 55, 期 9, 页码 747-755出版社
WILEY-BLACKWELL
DOI: 10.1002/ajim.22085
关键词
glioma; case-control studies; occupation; industry; occupational exposure
资金
- NIOSH Initiative for Cancer Control Projects for Farmers
- CDC/NIOSH
Background Understanding glioma etiology requires determining which environmental factors are associated with glioma. Upper Midwest Health Study casecontrol participant work histories collected 19951998 were evaluated for occupational associations with glioma. Exposures of interest from our study protocol comprise our a priori hypotheses. Materials and Methods Year-long or longer jobs for 1,973 participants were assigned Standard Occupational Classifications (SOC) and Standard Industrial Classifications (SIC). The analysis file includes 8,078 SIC- and SOC-coded jobs. For each individual, SAS 9.2 programs collated employment with identical SIC-SOC coding. Distributions of longest total employment duration (total years worked in jobs with identical industry and occupation codes, including multiple jobs, and non-consecutive jobs) were compared between cases and controls, using an industrial hygiene algorithm to group occupations. Results Longest employment duration was calculated for 780 cases and 1,156 controls. More case than control longest total employment duration was in the engineer, architect occupational group [16 cases, 10 controls, odds ratio (OR) 2.50, adjusted for age group, sex, age and education, 95% confidence interval (CI) 1.125.60]. Employment as a food processing worker [mostly butchers and meat cutters] was of borderline significance (27 cases, 21 controls, adjusted OR: 1.78, CI: 0.993.18). Conclusions Among our exposures of interest work as engineers or as butchers and meat cutters was associated with increased glioma risk. Significant associations could be due to chance, because of multiple comparisons, but similar findings have been reported for other glioma studies. Our results suggest some possible associations but by themselves could not provide conclusive evidence. Am. J. Ind. Med. 55:747755, 2012. (c) 2012 Wiley Periodicals, Inc.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据