期刊
AMERICAN JOURNAL OF HUMAN GENETICS
卷 90, 期 5, 页码 915-924出版社
CELL PRESS
DOI: 10.1016/j.ajhg.2012.04.003
关键词
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资金
- Marie Curie Early Stage Training Advanced Genetic Analysis in the Post-genomic Era (European Union) [MEST-CT-2004-504318]
- Newton International Fellowship
- Italian Ministry of Education, University, and Research
- Fondazione Alma Mater Ticinensis
- European Commission, Directorate-General for Research [205419]
- European Union through the Centre of Excellence in Genomics
- Estonian Ministry of Education and Research [SF 0270177As08, SF 0270177Bs08]
- Estonian Science Foundation [7858]
- FCT (Portuguese Foundation for Science and Technology) [PTDC/CS-ANT/113832/2009, SFRH/BD/45657/2008, SFRH/BPD/64233/2009]
- DeLaszlo Foundation
- Institute of International Education
- FCT
- Fundação para a Ciência e a Tecnologia [PTDC/CS-ANT/113832/2009, SFRH/BD/45657/2008] Funding Source: FCT
Human populations, along with those of many other species, are thought to have contracted into a number of refuge areas at the height of the last Ice Age. European populations are believed to be, to a large extent, the descendants of the inhabitants of these refugia, and some extant mtDNA lineages can be traced to refugia in Franco-Cantabria (haplogroups Ell, H3, V, and U5b1), the Italian Peninsula (U5b3), and the East European Plain (U4 and U5a). Parts of the Near East, such as the Levant, were also continuously inhabited throughout the Last Glacial Maximum, but unlike western and eastern Europe, no archaeological or genetic evidence for Late Glacial expansions into Europe from the Near East has hitherto been discovered. Here we report, on the basis of an enlarged whole-genome mitochondrial database, that a substantial, perhaps predominant, signal from mitochondrial haplogroups J and T, previously thought to have spread primarily from the Near East into Europe with the Neolithic population, may in fact reflect dispersals during the Late Glacial period, similar to 19-12 thousand years (ka) ago.
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