期刊
AMERICAN JOURNAL OF HOSPICE & PALLIATIVE MEDICINE
卷 25, 期 5, 页码 407-411出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/1049909108315518
关键词
cancer; cytokines; cancer-related cachexia; anorexia; tissue wasting
Cancer anorexia cachexia syndrome is frequent yet still a not well understood cancer-related problem. The pathophysiology of cancer cachexia is multifactorial. It is suggested to be the result of tumor-host interactions and studies of the disturbances seen during cancer anorexia cachexia syndrome, such as anorexia, hypermetabolism, tissue wasting, metabolic abnormalities, and hormonal changes, all point to the involvement in one way or another of one key factor: cytokines. The purpose of this review is to summarize the latest developments in the field of cytokines and their role in cancer anorexia cachexia syndrome. The emphasis is on the role of cytokines in anorexia and tissue wasting.
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