期刊
AMERICAN JOURNAL OF FORENSIC MEDICINE AND PATHOLOGY
卷 30, 期 2, 页码 209-214出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/PAF.0b013e3181873c7d
关键词
Sudden death; cardiomyopathy; left ventricle; fibrosis; fibrofatty replacement
We report 5 cases Of Sudden cardiac death, with similar cardiac findings. All 5 cases had circumferential left ventricular subepicardial fibrofatty replacement of the myocardium, similar to the histologic features of arrhythmogenic right ventricular cardiomyopathy (ARVC). In these cases, the findings were predominantly in the left ventricle with minimal or no involvement of the right ventricle. Four of the 5 cases had siblings with either sudden death or cardiac symptoms. This report highlights 5 cases of sudden death in the young with histologic findings similar to ARVC, with predominant left ventricular involvement and questions whether the cases represent a larger spectrum of the cardiomyopathy known as ARVC. which perhaps should be more correctly termed as arrhythmogenic cardiomyopathy or represent a separate, potentially inheritable cardiomyopathic entity. We report these cases to familiarize forensic pathologists With this uncommon and potentially inheritable condition.
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