期刊
AMERICAN JOURNAL OF EPIDEMIOLOGY
卷 173, 期 3, 页码 282-291出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/aje/kwq365
关键词
eating; factor analysis; mental recall; neoplasms; germ cell and embryonal; prenatal nutritional physiological phenomena
资金
- NCI NIH HHS [U10 CA98413, U10 CA98543, U10 CA098413, U10 CA098543, U54 CA163069, T32 CA099936] Funding Source: Medline
- NIMHD NIH HHS [U54 MD007593] Funding Source: Medline
Maternal diet during pregnancy may be associated with cancer in offspring. Intake of individual foods, as well as dietary patterns, can be used when examining these relations. Here, the authors examined associations between maternal dietary intake patterns and pediatric germ cell tumors (GCTs) using principal components analysis and logistic regression. Mothers of 222 GCT cases aged less than 15 years who were diagnosed at a Children's Oncology Group institution between 1993 and 2001 and those of 336 frequency-matched controls completed a self-administered food frequency questionnaire of diet during early pregnancy. Four dietary patterns were identified: Western, fruits and vegetables, protein, and healthful. With adjustment for birth weight, parity, and vitamin use, the fruits and vegetables pattern was significantly associated with a lower odds for GCTs (odds ratio (OR) = 0.83, 95% confidence interval (CI): 0.69, 0.99; 2 sided). Upon stratification, the fruits and vegetables pattern was significantly associated with a lower odds in males (OR = 0.66, 95% CI: 0.47, 0.92) but not females (OR = 0.91, 95% CI: 0.72, 1.14). A quantitative assessment of assumed nondifferential reporting error indicated no notable deviations from unadjusted odds ratio estimates. Results of this exploratory analysis suggest that maternal prenatal dietary patterns could be considered in future studies of GCTs in offspring.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据