期刊
AMERICAN JOURNAL OF EPIDEMIOLOGY
卷 168, 期 1, 页码 98-104出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/aje/kwn120
关键词
bias (epidemiology); breast neoplasms; mass screening; models; statistical; survival
Determination of survival time among persons with screen-detected cancer is subject to lead time and length biases. The authors propose a simple correction for lead time, assuming an exponential distribution of the preclinical screen-detectable period. Assuming two latent categories of tumors, one of which is more prone to screen detection and correspondingly less prone to death from the cancer in question, the authors have developed a strategy of sensitivity analysis for various magnitudes of length bias. Here they demonstrate these methods using a series of 25,962 breast cancer cases (1988-2004) from the West Midlands, United Kingdom.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据