期刊
AMERICAN JOURNAL OF DERMATOPATHOLOGY
卷 31, 期 4, 页码 375-378出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/DAD.0b013e31818a5c37
关键词
aggressive digital papillary adenocarcinoma; digital squamous cell carcinoma; human papillomavirus-58; human papillomavirus-73
类别
Aggressive digital papillary adenocarcinoma (ADPA) is a rare tumor that is considered to arise from eccrine sweat glands of the skin. It occurs predominantly in men with a mean age in the sixth decade. It shows a strong tendency for local recurrence and has the potential to metastasize to distant sites. Prompt diagnosis and regular follow-tip are important to ensure the best possible outcome. We discuss a case of recurrent ADPA associated with subsequent squamous cell carcinoma (SCC) in different contralateral digits in a 55-year-old man. One SCC lesion tested positive for human papillomavirus (HPV)-58. HPV-associated digital SCCs have been reported; most cases are HPV-16 positive. This report describes a rare case of an HPV-58-positive invasive digital SCC and an HPV-73-positive SCC in situ associated with ADPA.
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