期刊
AMERICAN JOURNAL OF CLINICAL PATHOLOGY
卷 139, 期 3, 页码 275-288出版社
OXFORD UNIV PRESS INC
DOI: 10.1309/AJCPFO8IIDNBIJ8Y
关键词
Glioma; EGFR; 1p/19q; BRAF; IDH1/2; MGMT
类别
资金
- National Cancer Institute [1-K08 CA155764-01A1]
- National Institute of General Medical Sciences [2P20 RR020171]
- University of Kentucky College of Medicine Physician Scientist Program
Advances in genetics research have greatly expanded our ability to accurately diagnose gliomas and provide more useful prognostic information. Herein specific examples are used to show how high-yield targets such as EGFR, 1p/19q, IDH1/2, MGMT, and BRAF can expand the power of the surgical neuropathologist. To avoid errors, however, the significance and controversies associated with each test must be thoroughly understood.
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