期刊
AMERICAN JOURNAL OF CLINICAL NUTRITION
卷 92, 期 4, 页码 912-921出版社
OXFORD UNIV PRESS
DOI: 10.3945/ajcn.2010.29482
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资金
- European Union [2005328]
- European Commission
- Research Directorate-General
- Ligue contre le Cancer
- Societe 3M
- Mutuelle Generale de l'Education Nationale
- Institut National de la Sante et de la Recherche Medicate (France)
- German Cancer Aid
- German Cancer Research Center
- Federal Ministry of Education and Research (Germany)
- Danish Cancer Society (Denmark)
- Spanish Ministry of Health [RD06/0020]
- Participating regional governments and institutions (Spain)
- Cancer Research United Kingdom
- Medical Research Council
- Stroke Association
- British Heart Foundation
- Department of Health
- Greek Ministry of Health and Social Solidarity
- Hellenic Health Foundation
- Stavros Niarchos Foundation (Greece)
- Italian Association for Research on Cancer
- National Research Council (Italy)
- Dutch Ministry of Public Health, Welfare and Sports
- Dutch Ministry of Health
- Dutch Prevention Funds
- LK Research Funds
- Dutch Zorg Onderzoek Nederland
- World Cancer Research Fund (Netherlands)
- Swedish Cancer Society
- Swedish Scientific Council
- Regional Government of Skane (Sweden)
- Norwegian Cancer Society (Norway)
- Medical Research Council [MC_U106179471] Funding Source: researchfish
Background: There is an association between a greater adherence to a Mediterranean diet and a reduced risk of developing chronic diseases. However, it is not clear whether this dietary pattern may be protective also against the development of obesity. Objective: We assessed the association between the adherence to the Mediterranean dietary pattern (MDP), prospective weight change, and the incidence of overweight or obesity. Design: We conducted a prospective cohort study [the European Prospective Investigation into Cancer and Nutrition Physical Activity, Nutrition, Alcohol Consumption, Cessation of Smoking, Eating Out of Home, and Obesity (EPIC-PANACEA) project] in 373,803 individuals (103,455 men and 270,348 women; age range: 25-70 y) from 10 European countries. Anthropometric measurements were obtained at recruitment and after a median follow-up time of 5 y. The relative Mediterranean Diet Score (rMED; score range: 0-18) was used to assess adherence to the MDP according to the consumption of 9 dietary components that are characteristic of the Mediterranean diet. The association between the rMED and 5-y weight change was modeled through multiadjusted mixed-effects linear regression. Results: Individuals with a high adherence to the MDP according to the rMED (11-18 points) showed a 5-y weight change of 0.16 kg (95% CI: 0.24, 0.07 kg) and were 10% (95% CI: 4%, 18%) less likely to develop overweight or obesity than were individuals with a low adherence to the MDP (0-6 points). The low meat content of the Mediterranean diet seemed to account for most of its positive effect against weight gain. Conclusion: This study shows that promoting the MDP as a model of healthy eating may help to prevent weight gain and the development of obesity. Am J Clin Nutr 2010;92:912-21.
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