期刊
ALZHEIMERS & DEMENTIA
卷 9, 期 3, 页码 332-337出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jalz.2012.06.004
关键词
Alzheimer's disease; Biomarkers; Magnetic resonance imaging; Analysis standards; ADNI
资金
- Alzheimer's Disease Neuroimaging Initiative (ADNI) (National Institutes of Health) [U01 AG024904]
- National Institute on Aging
- National Institute of Biomedical Imaging and Bioengineering
- ADNI clinical sites in Canada
- NIH [P30 AG010129, K01 AG030514]
- National Institute for Health Research [NF-SI-0508-10123] Funding Source: researchfish
The Alzheimer's Disease Neuroimaging Initiative (ADNI) three-dimensional T-1-weighted magnetic resonance imaging (MRI) acquisitions provide a rich data set for developing and testing analysis techniques for extracting structural endpoints. To promote greater rigor in analysis and meaningful comparison of different algorithms, the ADNI MRI Core has created standardized analysis sets of data comprising scans that met minimum quality control requirements. We encourage researchers to test and report their techniques against these data. Standard analysis sets of volumetric scans from ADNI-1 have been created, comprising screening visits, 1-year completers (subjects who all have screening, 6- and 12-month scans), 2-year annual completers (screening, 1-year and 2-year scans), 2-year completers (screening, 6-months, 1-year, 18-months [mild cognitive impaired (MCI) only], and 2-year scans), and complete visits (screening, 6-month, 1-year, 18-month [MCI only], 2-year, and 3-year [normal and MCI only] scans). As the ADNI-GO/ADNI-2 data become available, updated standard analysis sets will be posted regularly. (C) 2013 The Alzheimer's Association. All rights reserved.
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