期刊
ALZHEIMERS & DEMENTIA
卷 8, 期 1, 页码 1-13出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jalz.2011.10.007
关键词
Alzheimer's disease; Lewy body disease; Vascular brain injury; Neuropathology; Consensus guidelines
资金
- NIH [AG05134, AG05136, AG03991, AG05681, AG24904, AG28383, AG10161, AG17917, AG10124, AG13854, AG19610, NS62684, AG16570, AG15819, AG12435, AG05131, AG016976, AG18840]
- AA, Arizona Department of Health Services (Arizona Alzheimer's Consortium) [211002]
- Deutsche Forschungsgemeinschaft (DFG) [TH-624-4-1]
- Alzheimer Forschung Initiative (AFT) [10810]
- Nancy and Buster Alvord Endowment
- Charles and Joanne Knight Alzheimer Research Initiative
- NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE [P50NS062684] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE ON AGING [P50AG005681, U19AG010483, R01AG018440, P50AG005134, U19AG024904, R37AG018440, P50AG005136, U01AG024904, P01AG003949, U01AG016976, P50AG016570, RF1AG015819, P30AG028383, P50AG005131, P01AG012435, R01AG015819, P30AG019610, R01AG042210, P30AG013854, P30AG010161, P01AG003991, R01AG017917, P30AG010124] Funding Source: NIH RePORTER
A consensus panel from the United States and Europe was convened recently to update and revise the 1997 consensus guidelines for the neuropathologic evaluation of Alzheimer's disease (AD) and other diseases of brain that are common in the elderly. The new guidelines recognize the pre-clinical stage of AD, enhance the assessment of AD to include amyloid accumulation as well as neurofibrillary change and neuritic plaques, establish protocols for the neuropathologic assessment of Lewy body disease, vascular brain injury, hippocampal sclerosis, and TDP-43 inclusions, and recommend standard approaches for the workup of cases and their clinico-pathologic correlation. (C) 2012 The Alzheimer's Association. All rights reserved.
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